Today we'll look at three different methods of twain 80(also known as Twain 80 or Polysorbate 80) and Twain 20(also known as Twain 20) :
1. Synthesis of TWEN80 is based on the polymerization of dessaturated sorbitol monoleate to ethylene oxide. Synthesis of Tween 20: a mixture of polyethylene glycol and part of polyethylene glycol. Tween 80 is a polyol - type non - ionic surfactant. It is widely used in liquid, semi-solid and solid preparations, such as O/W emulsifiers, solvent-increasing, wetting, dispersing, stabilizing.
2. Tween 20 use: for disc condensation with ethylene oxide, because of its molecules have more hydrophilic, it has a strong hydrophilic, can be used as a non-ionic cleaner. Commonly used as O/W emulsifier, can be used with sodium dodecyl sulfate or SPAN emulsifier to improve the stability of the emulsion. It can also be used as a solvent solvent for some drugs. Characteristics of Twain 80: The peroxide value of Twain 80 is not more than 10, light yellow to orange mucus; A bit smelly. A slight bitterness, with a warmth. Soluble in water, ethanol, methanol or ethyl acetate, dissolved in mineral oil.
Characteristic: Twain 20 is a yellow or amber transparent oily liquid with a distinctive smell and a light bitter taste. Relative density 1.01, boiling point >; 100°C, Flash point 321°C, refractive index 1.472, viscosity (25°C)0.25≤0.40 pars.